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Development of a New DNA Vaccine for Alzheimer Disease Targeting a Wide Range of Aβ Species and Amyloidogenic Peptides

It has recently been determined that not only Aβ oligomers, but also other Aβ species and amyloidogenic peptides are neurotoxic in Alzheimer disease (AD) and play a pivotal role in AD pathogenesis. In the present study, we attempted to develop new DNA vaccines targeting a wide range of Aβ species. F...

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Detalhes bibliográficos
Main Authors: Matsumoto, Yoh, Niimi, Naoko, Kohyama, Kuniko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785508/
https://ncbi.nlm.nih.gov/pubmed/24086465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075203
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