Association of Promoter Methylation of VGF and PGP9.5 with Ovarian Cancer Progression

PURPOSE: To elucidate the role of biological and clinical impact of aberrant promoter hypermethylation (PH) in ovarian cancer (OC). EXPERIMENTAL DESIGN: PH of PGP9.5, HIC1, AIM1, APC, PAK3, MGMT, KIF1A, CCNA1, ESR1, SSBP2, GSTP1, FKBP4 and VGF were assessed by quantitative methylation specific PCR (...

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Hauptverfasser: Brait, Mariana, Maldonado, Leonel, Noordhuis, Maartje, Begum, Shahnaz, Loyo, Myriam, Poeta, Maria Luana, Barbosa, Alvaro, Fazio, Vito M., Angioli, Roberto, Rabitti, Carla, Marchionni, Luigi, de Graeff, Pauline, J. van der Zee, Ate G., Wisman, G. Bea A., Sidransky, David, Hoque, Mohammad O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785492/
https://ncbi.nlm.nih.gov/pubmed/24086249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070878
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