Association of Promoter Methylation of VGF and PGP9.5 with Ovarian Cancer Progression

PURPOSE: To elucidate the role of biological and clinical impact of aberrant promoter hypermethylation (PH) in ovarian cancer (OC). EXPERIMENTAL DESIGN: PH of PGP9.5, HIC1, AIM1, APC, PAK3, MGMT, KIF1A, CCNA1, ESR1, SSBP2, GSTP1, FKBP4 and VGF were assessed by quantitative methylation specific PCR (...

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Autors principals: Brait, Mariana, Maldonado, Leonel, Noordhuis, Maartje, Begum, Shahnaz, Loyo, Myriam, Poeta, Maria Luana, Barbosa, Alvaro, Fazio, Vito M., Angioli, Roberto, Rabitti, Carla, Marchionni, Luigi, de Graeff, Pauline, J. van der Zee, Ate G., Wisman, G. Bea A., Sidransky, David, Hoque, Mohammad O.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785492/
https://ncbi.nlm.nih.gov/pubmed/24086249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070878
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