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Association of Promoter Methylation of VGF and PGP9.5 with Ovarian Cancer Progression

PURPOSE: To elucidate the role of biological and clinical impact of aberrant promoter hypermethylation (PH) in ovarian cancer (OC). EXPERIMENTAL DESIGN: PH of PGP9.5, HIC1, AIM1, APC, PAK3, MGMT, KIF1A, CCNA1, ESR1, SSBP2, GSTP1, FKBP4 and VGF were assessed by quantitative methylation specific PCR (...

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Detalhes bibliográficos
Principais autores: Brait, Mariana, Maldonado, Leonel, Noordhuis, Maartje, Begum, Shahnaz, Loyo, Myriam, Poeta, Maria Luana, Barbosa, Alvaro, Fazio, Vito M., Angioli, Roberto, Rabitti, Carla, Marchionni, Luigi, de Graeff, Pauline, J. van der Zee, Ate G., Wisman, G. Bea A., Sidransky, David, Hoque, Mohammad O.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785492/
https://ncbi.nlm.nih.gov/pubmed/24086249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070878
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