Commensal Microbiota Contributes to Chronic Endocarditis in TAX1BP1 Deficient Mice

Tax1-binding protein 1 (Tax1bp1) negatively regulates NF-κB by editing the ubiquitylation of target molecules by its catalytic partner A20. Genetically engineered TAX1BP1-deficient (KO) mice develop age-dependent inflammatory constitutions in multiple organs manifested as valvulitis or dermatitis an...

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Autores principales: Nakano, Satoko, Ikebe, Emi, Tsukamoto, Yoshiyuki, Wang, Yan, Matsumoto, Takashi, Mitsui, Takahiro, Yahiro, Takaaki, Inoue, Kunimitsu, Kawazato, Hiroaki, Yasuda, Aiko, Ito, Kanako, Yokoyama, Shigeo, Takahashi, Naohiko, Hori, Mitsuo, Shimada, Tatsuo, Moriyama, Masatsugu, Kubota, Toshiaki, Ono, Katsushige, Fujibuchi, Wataru, Jeang, Kuan-Teh, Iha, Hidekatsu, Nishizono, Akira
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785488/
https://ncbi.nlm.nih.gov/pubmed/24086273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073205
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