Evidence for NF-κB- and CBP-Independent Repression of p53's Transcriptional Activity by Human T-Cell Leukemia Virus Type 1 Tax in Mouse Embryo and Primary Human Fibroblasts

The human T-cell leukemia virus type 1 (HTLV-1) Tax oncoprotein can repress the transcriptional activity of the tumor suppressor protein p53. However, it remains controversial whether Tax requires NF-κB factors/activity and/or p300/CBP in order to inactivate p53 function. To address this issue, we h...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Miyazato, Akiko, Sheleg, Sergey, Iha, Hidekatsu, Li, Yan, Jeang, Kuan-Teh
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2005
נושאים:
Virus-Cell Interactions
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168794/
https://ncbi.nlm.nih.gov/pubmed/15994832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.14.9346-9350.2005
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