Platelet Activating Factor-Induced Ceramide Micro-Domains Drive Endothelial NOS Activation and Contribute to Barrier Dysfunction

The spatial and functional relationship between platelet activating factor-receptor (PAF-R) and nitric oxide synthase (eNOS) in the lateral plane of the endothelial plasma membrane is poorly characterized. In this study, we used intact mouse pulmonary endothelial cells (ECs) as well as endothelial p...

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Main Authors: Predescu, Sanda, Knezevic, Ivana, Bardita, Cristina, Neamu, Radu Florin, Brovcovych, Viktor, Predescu, Dan
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785431/
https://ncbi.nlm.nih.gov/pubmed/24086643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075846
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