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Platelet Activating Factor-Induced Ceramide Micro-Domains Drive Endothelial NOS Activation and Contribute to Barrier Dysfunction

The spatial and functional relationship between platelet activating factor-receptor (PAF-R) and nitric oxide synthase (eNOS) in the lateral plane of the endothelial plasma membrane is poorly characterized. In this study, we used intact mouse pulmonary endothelial cells (ECs) as well as endothelial p...

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Détails bibliographiques
Auteurs principaux: Predescu, Sanda, Knezevic, Ivana, Bardita, Cristina, Neamu, Radu Florin, Brovcovych, Viktor, Predescu, Dan
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785431/
https://ncbi.nlm.nih.gov/pubmed/24086643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075846
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