Immunosuppressants Affect Human Neural Stem Cells In Vitro but Not in an In Vivo Model of Spinal Cord Injury

Clinical immunosuppression protocols use calcineurin inhibitors, such as cyclosporine A (CsA) or tacrolimus (FK506), or mammalian target of rapamycin (mTOR) inhibitors, such as sirolimus (rapamycin). These compounds alter immunophilin ligand signaling pathways, which are known to interact downstream...

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Detalles Bibliográficos
Main Authors: Sontag, Christopher J., Nguyen, Hal X., Kamei, Noriko, Uchida, Nobuko, Anderson, Aileen J., Cummings, Brian J.
Formato: Artigo
Idioma:Inglês
Publicado: AlphaMed Press 2013
Assuntos:
Fetal and Neonatal Stem Cells
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785258/
https://ncbi.nlm.nih.gov/pubmed/23981724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2012-0175
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