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Dysregulation of serine biosynthesis contributes to the growth defect of a Mycobacterium tuberculosis crp mutant
Mycobacterium tuberculosis CRP(Mt), encoded by Rv3676 (crp), is a CRP-like transcription factor that binds with the serC – Rv0885 intergenic region. In the present study, we evaluated CRP(Mt)’s regulation of serC and Rv0885 in M. tuberculosis and M. bovis BCG, using site-specific mutagenesis, promot...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3785234/ https://ncbi.nlm.nih.gov/pubmed/21902733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2011.07806.x |
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