Abnormal functional and morphological regulation of the gastric mucosa in histamine H2 receptor–deficient mice
To clarify the physiological roles of histamine H2 receptor (H2R), we have generated histamine H2R-deficient mice by gene targeting. Homozygous mutant mice were viable and fertile without apparent abnormalities and, unexpectedly, showed normal basal gastric pH. However, the H2R-deficient mice exhibi...
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| Yayımlandı: | J Clin Invest |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Clinical Investigation
2000
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC378512/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10862789/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI9441 |
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