In vivo and in silico pharmacokinetics and biodistribution of a melanocortin receptor 1 targeted agent in preclinical models of melanoma

The melanocortin 1 receptor (MC1R) is overexpressed in most melanoma metastases, making it a promising target for imaging of melanomas. In this study, the expression of MC1R in a large fraction of patients with melanoma was confirmed using mRNA and tissue microarray. Here, we have characterized the...

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Detaylı Bibliyografya
Asıl Yazarlar: Tafreshi, Narges K, Silva, Ariosto, Estrella, Veronica C, McCardle, Timothy W, Chen, Tingan, Jeune-Smith, Yolaine, Lloyd, Mark C, Enkemann, Steven A, Smalley, Keiran SM, Sondak, Vernon K, Vagner, Josef, Morse, David L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785103/
https://ncbi.nlm.nih.gov/pubmed/23763620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp400222j
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