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CCR7 Plays No Appreciable Role in Trafficking of Central Memory CD4 T Cells to Lymph Nodes
CCR7(−/−) mice exhibit profound anomalies in LN and spleen architecture, which complicates the study of CCR7-mediated T cell trafficking in vivo. To circumvent this problem, we established in vivo models in which WT and CCR7(−/−) populations coexist within mice possessing normal lymphoid organs, and...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3784989/ https://ncbi.nlm.nih.gov/pubmed/23935190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200938 |
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