CCR7 Plays No Appreciable Role in Trafficking of Central Memory CD4 T Cells to Lymph Nodes

CCR7(−/−) mice exhibit profound anomalies in LN and spleen architecture, which complicates the study of CCR7-mediated T cell trafficking in vivo. To circumvent this problem, we established in vivo models in which WT and CCR7(−/−) populations coexist within mice possessing normal lymphoid organs, and...

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Bibliographic Details
Main Authors: Lugt, Bryan Vander, Tubo, Noah J., Nizza, Suzanne T., Boes, Marianne, Malissen, Bernard, Fuhlbrigge, Robert C., Kupper, Thomas S., Campbell, James J.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784989/
https://ncbi.nlm.nih.gov/pubmed/23935190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200938
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