Coordinate Functional Regulation between Microsomal Prostaglandin E Synthase-1 (mPGES-1) and Peroxisome Proliferator-activated Receptor γ (PPARγ) in the Conversion of White-to-brown Adipocytes

Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated nuclear receptor and a master regulator of adipogenesis. Microsomal prostaglandin E (PGE) synthase-1 (mPGES-1) is an inducible enzyme that couples with cyclooxygenase-2 for the biosynthesis of PGE(2). In this study we demonst...

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Detalhes bibliográficos
Main Authors: García-Alonso, Verónica, López-Vicario, Cristina, Titos, Esther, Morán-Salvador, Eva, González-Périz, Ana, Rius, Bibiana, Párrizas, Marcelina, Werz, Oliver, Arroyo, Vicente, Clària, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784732/
https://ncbi.nlm.nih.gov/pubmed/23943621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.468603
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