Spectrin Domain of Eukaryotic Initiation Factor 3a Is the Docking Site for Formation of the a:b:i:g Subcomplex

eIF3a (eukaryotic translation initiation factor 3a), one of the core subunits of the eIF3 complex, has been implicated in regulating translation of different mRNAs and in tumorigenesis. A subcomplex consisting of eIF3a, eIF3b, eIF3g, and eIF3i (eIF3(a:b:i:g)) has also been identified. However, how e...

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Hlavní autoři: Dong, Zizheng, Qi, Jing, Peng, Hui, Liu, Jianguo, Zhang, Jian-Ting
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Protein Synthesis and Degradation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784709/
https://ncbi.nlm.nih.gov/pubmed/23921387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.483164
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