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Knockdown of Cyclin-dependent Kinase 10 (cdk10) Gene Impairs Neural Progenitor Survival via Modulation of raf1a Gene Expression

In this study, we used zebrafish as an animal model to elucidate the developmental function of cdk10 in vertebrates. In situ hybridization analyses demonstrated that cdk10 is expressed throughout development with a relative enrichment in the brain in the late stages. Similar to its mammalian ortholo...

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Bibliographic Details
Main Authors: Yeh, Chi-Wei, Kao, Shoa-Hsuan, Cheng, Yi-Chuan, Hsu, Li-Sung
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784707/
https://ncbi.nlm.nih.gov/pubmed/23902762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.420265
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