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Metformin Inhibits Follicle-Stimulating Hormone (FSH) Action in Human Granulosa Cells: Relevance to Polycystic Ovary Syndrome

BACKGROUND: Women with anovulatory polycystic ovary syndrome (PCOS) are generally insulin-resistant and as a consequence are often treated with the biguanide metformin. Results with metformin have, however, been variable with some studies demonstrating induction of regular cycles and an increase in...

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Detalhes bibliográficos
Main Authors: Rice, Suman, Elia, Androulla, Jawad, Zara, Pellatt, Laura, Mason, Helen D.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784648/
https://ncbi.nlm.nih.gov/pubmed/23846817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-1865
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