Association between MGMT Promoter Methylation and Non-Small Cell Lung Cancer: A Meta-Analysis

BACKGROUND: O(6)-methylguanine-DNA methyltransferase (MGMT) is one of most important DNA repair enzyme against common carcinogens such as alkylate and tobacco. Aberrant promoter methylation of the gene is frequently observed in non-small cell lung cancer (NSCLC). However, the importance of epigeneti...

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Autores principales: Gu, Changmei, Lu, Jiachun, Cui, Tianpen, Lu, Cheng, Shi, Hao, Xu, Wenmao, Yuan, Xueli, Yang, Xiaobo, Huang, Yangxin, Lu, Meixia
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784462/
https://ncbi.nlm.nih.gov/pubmed/24086261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072633
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