Therapeutic Potential of the Translation Inhibitor Silvestrol in Hepatocellular Cancer

BACKGROUND & AIMS: Although hepatocellular cancers (HCC) frequently arise in the setting of fibrosis and a hepatic regenerative response requiring new cell growth, therapeutic strategies for these cancers have not targeted protein synthesis. Silvestrol, a rocaglate isolated from Aglaia foveolata...

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Hauptverfasser: Kogure, Takayuki, Kinghorn, A. Douglas, Yan, Irene, Bolon, Brad, Lucas, David M., Grever, Michael R., Patel, Tushar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784426/
https://ncbi.nlm.nih.gov/pubmed/24086701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076136
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