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Clinical relevance of cancer stem cells in bone marrow of early breast cancer patients

BACKGROUND: Cancer stem cells (CSCs) are epithelial tumor cells that express CD44(+)CD24(−/lo). CSCs can be further divided into those that have aldehyde dehydrogenase (ALDH) activity (Aldefluor(+)) and those that do not. We hypothesized that if CSCs are responsible for tumor dissemination, their pr...

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Detalhes bibliográficos
Main Authors: Giordano, A., Gao, H., Cohen, E. N., Anfossi, S., Khoury, J., Hess, K., Krishnamurthy, S., Tin, S., Cristofanilli, M., Hortobagyi, G. N., Woodward, W. A., Lucci, A., Reuben, J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784333/
https://ncbi.nlm.nih.gov/pubmed/23798614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdt223
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