Altered Ca(2+) concentration, permeability and buffering in the myofibre Ca(2+) store of a mouse model of malignant hyperthermia

Malignant hyperthermia (MH) is linked to mutations in the type 1 ryanodine receptor, RyR1, the Ca(2+) channel of the sarcoplasmic reticulum (SR) of skeletal muscle. The Y522S MH mutation was studied for its complex presentation, which includes structurally and functionally altered cell ‘cores’. Imag...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Manno, Carlo, Figueroa, Lourdes, Royer, Leandro, Pouvreau, Sandrine, Lee, Chang Seok, Volpe, Pompeo, Nori, Alessandra, Zhou, Jingsong, Meissner, Gerhard, Hamilton, Susan L, Ríos, Eduardo
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Blackwell Science Inc 2013
Θέματα:
Molecular and Cellular
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784192/
https://ncbi.nlm.nih.gov/pubmed/23798496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.259572
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