A novel recombinant DNA vaccine encoding Mycobacterium tuberculosis ESAT-6 and FL protects against Mycobacterium tuberculosis challenge in mice

Mycobacterium tuberculosis 6-kDa early secretory antigenic target (ESAT-6) is a dominant target antigen for cell-mediated immunity in the early phase of tuberculosis. The fms-like tyrosine kinase 3 ligand (FL) that induces potent immune response has been used as an adjuvant in vaccine development. I...

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Detalhes bibliográficos
Main Authors: Jiang, Qingtao, Zhang, Jing, Chen, Xia, Xia, Mei, Lu, Yanlai, Qiu, Wen, Feng, Ganzhu, Zhao, Dan, Li, Yan, He, Fengxia, Peng, Guangyong, Wang, Yingwei
Formato: Artigo
Idioma:Inglês
Publicado em: Editorial Department of Journal of Biomedical Research 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783826/
https://ncbi.nlm.nih.gov/pubmed/24086174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7555/JBR.27.20120114
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