Preclinical study and phase I clinical safety evaluation of recombinant Mycobacterium tuberculosis ESAT6 protein

BACKGROUND: To investigate the ability of rESAT6 to identify different mycobacteria-sensitized guinea pigs and its safety in preclinical and phase I clinical study. MATERIAL/METHODS: Guinea pigs were sensitized with different Mycobacteria. After sensitization, all animals were intradermally injected...

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Detalhes bibliográficos
Main Authors: Du, Wei-Xin, Chen, Bao-Wen, Lu, Jin-Biao, Gao, Meng-Qiu, Shen, Xiao-Bing, Yang, Lei, Su, Cheng, Wang, Guo-Zhi, Sun, Qing-feng, Xu, Miao
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2013
Assuntos:
Animal Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659126/
https://ncbi.nlm.nih.gov/pubmed/23676766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSMBR.883912
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