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The Non-Protein Amino Acid BMAA Is Misincorporated into Human Proteins in Place of l-Serine Causing Protein Misfolding and Aggregation

Mechanisms of protein misfolding are of increasing interest in the aetiology of neurodegenerative diseases characterized by protein aggregation and tangles including Amyotrophic Lateral Sclerosis (ALS), Alzheimer’s disease (AD), Parkinson’s disease (PD), Lewy Body Dementia (LBD), and Progressive Sup...

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Detalhes bibliográficos
Main Authors: Dunlop, Rachael Anne, Cox, Paul Alan, Banack, Sandra Anne, Rodgers, Kenneth John
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783393/
https://ncbi.nlm.nih.gov/pubmed/24086518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075376
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