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The Non-Protein Amino Acid BMAA Is Misincorporated into Human Proteins in Place of l-Serine Causing Protein Misfolding and Aggregation

Mechanisms of protein misfolding are of increasing interest in the aetiology of neurodegenerative diseases characterized by protein aggregation and tangles including Amyotrophic Lateral Sclerosis (ALS), Alzheimer’s disease (AD), Parkinson’s disease (PD), Lewy Body Dementia (LBD), and Progressive Sup...

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Autori principali: Dunlop, Rachael Anne, Cox, Paul Alan, Banack, Sandra Anne, Rodgers, Kenneth John
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783393/
https://ncbi.nlm.nih.gov/pubmed/24086518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075376
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