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Efficient Design for Mendelian Randomization Studies: Subsample and 2-Sample Instrumental Variable Estimators

Mendelian randomization (MR) is a method for estimating the causal relationship between an exposure and an outcome using a genetic factor as an instrumental variable (IV) for the exposure. In the traditional MR setting, data on the IV, exposure, and outcome are available for all participants. Howeve...

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Bibliografski detalji
Glavni autori: Pierce, Brandon L., Burgess, Stephen
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783091/
https://ncbi.nlm.nih.gov/pubmed/23863760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwt084
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