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Credible Mendelian Randomization Studies: Approaches for Evaluating the Instrumental Variable Assumptions

As with other instrumental variable (IV) analyses, Mendelian randomization (MR) studies rest on strong assumptions. These assumptions are not routinely systematically evaluated in MR applications, although such evaluation could add to the credibility of MR analyses. In this article, the authors pres...

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Detalhes bibliográficos
Main Authors: Glymour, M. Maria, Tchetgen Tchetgen, Eric J., Robins, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366596/
https://ncbi.nlm.nih.gov/pubmed/22247045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwr323
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