Highly Efficient Retrograde Gene Transfer into Motor Neurons by a Lentiviral Vector Pseudotyped with Fusion Glycoprotein

The development of gene therapy techniques to introduce transgenes that promote neuronal survival and protection provides effective therapeutic approaches for neurological and neurodegenerative diseases. Intramuscular injection of adenoviral and adeno-associated viral vectors, as well as lentiviral...

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Bibliographic Details
Main Authors: Hirano, Miyabi, Kato, Shigeki, Kobayashi, Kenta, Okada, Tomoaki, Yaginuma, Hiroyuki, Kobayashi, Kazuto
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782444/
https://ncbi.nlm.nih.gov/pubmed/24086660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075896
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