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Platelets and Alzheimer’s disease: Potential of APP as a biomarker

Platelets are the first peripheral source of amyloid precursor protein (APP). They possess the proteolytic machinery to produce Aβ and fragments similar to those produced in neurons, and thus offer an ex-vivo model to study APP processing and changes associated with Alzheimer’s disease (AD). Platele...

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Hlavní autoři: Evin, Geneviève, Li, Qiao-Xin
Médium: Artigo
Jazyk:Inglês
Vydáno: Baishideng Publishing Group Co., Limited 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782192/
https://ncbi.nlm.nih.gov/pubmed/24175176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5498/wjp.v2.i6.102
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