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Platelets and Alzheimer’s disease: Potential of APP as a biomarker
Platelets are the first peripheral source of amyloid precursor protein (APP). They possess the proteolytic machinery to produce Aβ and fragments similar to those produced in neurons, and thus offer an ex-vivo model to study APP processing and changes associated with Alzheimer’s disease (AD). Platele...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Baishideng Publishing Group Co., Limited
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3782192/ https://ncbi.nlm.nih.gov/pubmed/24175176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5498/wjp.v2.i6.102 |
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