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CD4(+) T cells are trigger and target of the glucocorticoid response that prevents lethal immunopathology in toxoplasma infection

Synthetic glucocorticoids (GCs) are commonly used in the treatment of inflammatory diseases, but the role of endogenous GCs in the regulation of host-protective immune responses is poorly understood. Here we show that GCs are induced during acute Toxoplasma gondii infection and directly control the...

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Bibliografiske detaljer
Main Authors: Kugler, David G., Mittelstadt, Paul R., Ashwell, Jonathan D., Sher, Alan, Jankovic, Dragana
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782051/
https://ncbi.nlm.nih.gov/pubmed/23980098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20122300
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