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Peptide-based anticancer vaccines: The making and unmaking of a T-cell graveyard
Poorly biodegradable, incomplete Freund’s adjuvant (IFA)-based anticancer vaccines primed CD8(+) T cells that did not localize to the tumor site but to the persisting, antigen-rich vaccination site, which became a T-cell graveyard. Short-lived, water-based formulations and the provision of immunosti...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3782014/ https://ncbi.nlm.nih.gov/pubmed/24073366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.24743 |
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