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Predicting Functionally Informative Mutations in Escherichia coli BamA Using Evolutionary Covariance Analysis
The essential outer membrane β-barrel protein BamA forms a complex with four lipoprotein partners BamBCDE that assembles β-barrel proteins into the outer membrane of Escherichia coli. Detailed genetic studies have shown that BamA cycles through multiple conformations during substrate assembly, sugge...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3781972/ https://ncbi.nlm.nih.gov/pubmed/23934888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.155861 |
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