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Spargel/dPGC-1 Is a New Downstream Effector in the Insulin–TOR Signaling Pathway in Drosophila
Insulin and target of rapamycin (TOR) signaling pathways converge to maintain growth so a proportionate body form is attained. Insufficiency in either insulin or TOR results in developmental growth defects due to low ATP level. Spargel is the Drosophila homolog of PGC-1, which is an omnipotent trans...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Genetics Society of America
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3781971/ https://ncbi.nlm.nih.gov/pubmed/23934892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.154583 |
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