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Development of gene therapy: potential in severe combined immunodeficiency due to adenosine deaminase deficiency

The history of stem cell gene therapy is strongly linked to the development of gene therapy for severe combined immunodeficiencies (SCID) and especially adenosine deaminase (ADA)-deficient SCID. Here we discuss the developments achieved in over two decades of clinical and laboratory research that le...

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Detalhes bibliográficos
Main Authors: Montiel-Equihua, Claudia A, Thrasher, Adrian J, Gaspar, H Bobby
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781725/
https://ncbi.nlm.nih.gov/pubmed/24198507
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