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Novel Hypothesis to Explain Why SGLT2 Inhibitors Inhibit Only 30–50% of Filtered Glucose Load in Humans

Inhibitors of sodium-glucose cotransporter 2 (SGLT2) are a novel class of antidiabetes drugs, and members of this class are under various stages of clinical development for the management of type 2 diabetes mellitus (T2DM). It is widely accepted that SGLT2 is responsible for >80% of the reabsorpt...

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Autors principals: Abdul-Ghani, Muhammad A., DeFronzo, Ralph A., Norton, Luke
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781482/
https://ncbi.nlm.nih.gov/pubmed/24065789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0604
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