Loss of Prohibitin Induces Mitochondrial Damages Altering β-Cell Function and Survival and Is Responsible for Gradual Diabetes Development

Prohibitins are highly conserved proteins mainly implicated in the maintenance of mitochondrial function and architecture. Their dysfunctions are associated with aging, cancer, obesity, and inflammation. However, their possible role in pancreatic β-cells remains unknown. The current study documents...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Supale, Sachin, Thorel, Fabrizio, Merkwirth, Carsten, Gjinovci, Asllan, Herrera, Pedro L., Scorrano, Luca, Meda, Paolo, Langer, Thomas, Maechler, Pierre
التنسيق: Artigo
اللغة:Inglês
منشور في: American Diabetes Association 2013
الموضوعات:
Original Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781460/
https://ncbi.nlm.nih.gov/pubmed/23863811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0152
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