Mitochondrial dysfunction during loss of prohibitin 1 triggers Paneth cell defects and ileitis

OBJECTIVE: Although perturbations in mitochondrial function and structure have been described in the intestinal epithelium of Crohn’s disease and ulcerative colitis patients, the role of epithelial mitochondrial stress in the pathophysiology of inflammatory bowel diseases (IBD) is not well elucidate...

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Enregistré dans:
Détails bibliographiques
Publié dans:Gut
Auteurs principaux: Jackson, Dakota N, Panopoulos, Marina, Neumann, William L, Turner, Kevin, Cantarel, Brandi L, Thompson-Snipes, LuAnn, Dassopoulos, Themistocles, Feagins, Linda A, Souza, Rhonda F, Mills, Jason C, Blumberg, Richard S, Venuprasad, K, Thompson, Winston E, Theiss, Arianne L
Format: Artigo
Langue:Inglês
Publié: BMJ Publishing Group 2020
Sujets:
Inflammatory Bowel Disease
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483170/
https://ncbi.nlm.nih.gov/pubmed/32111635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2019-319523
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