Mitochondrial dysfunction during loss of prohibitin 1 triggers Paneth cell defects and ileitis

OBJECTIVE: Although perturbations in mitochondrial function and structure have been described in the intestinal epithelium of Crohn’s disease and ulcerative colitis patients, the role of epithelial mitochondrial stress in the pathophysiology of inflammatory bowel diseases (IBD) is not well elucidate...

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Bibliografische gegevens
Gepubliceerd in:Gut
Hoofdauteurs: Jackson, Dakota N, Panopoulos, Marina, Neumann, William L, Turner, Kevin, Cantarel, Brandi L, Thompson-Snipes, LuAnn, Dassopoulos, Themistocles, Feagins, Linda A, Souza, Rhonda F, Mills, Jason C, Blumberg, Richard S, Venuprasad, K, Thompson, Winston E, Theiss, Arianne L
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMJ Publishing Group 2020
Onderwerpen:
Inflammatory Bowel Disease
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483170/
https://ncbi.nlm.nih.gov/pubmed/32111635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2019-319523
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