Mitochondrial dysfunction during loss of prohibitin 1 triggers Paneth cell defects and ileitis

OBJECTIVE: Although perturbations in mitochondrial function and structure have been described in the intestinal epithelium of Crohn’s disease and ulcerative colitis patients, the role of epithelial mitochondrial stress in the pathophysiology of inflammatory bowel diseases (IBD) is not well elucidate...

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Sonraí Bibleagrafaíochta
Foilsithe in:Gut
Main Authors: Jackson, Dakota N, Panopoulos, Marina, Neumann, William L, Turner, Kevin, Cantarel, Brandi L, Thompson-Snipes, LuAnn, Dassopoulos, Themistocles, Feagins, Linda A, Souza, Rhonda F, Mills, Jason C, Blumberg, Richard S, Venuprasad, K, Thompson, Winston E, Theiss, Arianne L
Formáid: Artigo
Teanga:Inglês
Foilsithe: BMJ Publishing Group 2020
Ábhair:
Inflammatory Bowel Disease
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483170/
https://ncbi.nlm.nih.gov/pubmed/32111635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2019-319523
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