Mitochondrial dysfunction during loss of prohibitin 1 triggers Paneth cell defects and ileitis

OBJECTIVE: Although perturbations in mitochondrial function and structure have been described in the intestinal epithelium of Crohn’s disease and ulcerative colitis patients, the role of epithelial mitochondrial stress in the pathophysiology of inflammatory bowel diseases (IBD) is not well elucidate...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Jackson, Dakota N, Panopoulos, Marina, Neumann, William L, Turner, Kevin, Cantarel, Brandi L, Thompson-Snipes, LuAnn, Dassopoulos, Themistocles, Feagins, Linda A, Souza, Rhonda F, Mills, Jason C, Blumberg, Richard S, Venuprasad, K, Thompson, Winston E, Theiss, Arianne L
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Inflammatory Bowel Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483170/
https://ncbi.nlm.nih.gov/pubmed/32111635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2019-319523
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