Downregulation of Beclin1 and Impairment of Autophagy in a Small Population of Colorectal Cancer

BACKGROUND: Autophagy is a highly conserved mechanism for degradation and recycling of long-lived proteins and damaged organelle to maintain cell homeostasis. Deregulation of autophagy has been associated with tumorigenesis. Beclin 1 is an essential autophagy protein and its upregulation has been ob...

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Bibliografiske detaljer
Main Authors: Chen, Zhihong, Li, Yanchun, Zhang, Chi, Yi, Hongmei, Wu, Chang, Wang, Junpu, Liu, Yuwu, Tan, Jieqiong, Wen, Jifang
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2013
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781302/
https://ncbi.nlm.nih.gov/pubmed/23812859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-013-2732-8
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