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Metalloprotein-inhibitor binding: Human carbonic anhydrase II as a model for probing metal-ligand interactions in a metalloprotein active site

An ever increasing number of metalloproteins are being discovered that play essential roles in physiological processes. Inhibitors of these proteins have significant potential for the treatment of human disease, but clinical success of these compounds has been limited. Herein, Zn(II)-dependent metal...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Martin, David P., Hann, Zachary S., Cohen, Seth M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781179/
https://ncbi.nlm.nih.gov/pubmed/23706138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ic400295f
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