Secretoneurin Gene Therapy Improves Blood Flow in an Ischemia Model in Type 1 Diabetic Mice by Enhancing Therapeutic Neovascularization

Deficient angiogenesis after ischemia may contribute to worse outcome of peripheral arterial disease in patients with diabetes mellitus. Based on our previous work where we demonstrated that Secretoneurin (SN) is up-regulated under hypoxic conditions and enhances angiogenesis, we analyzed the therap...

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Bibliographische Detailangaben
Hauptverfasser: Schgoer, Wilfried, Theurl, Markus, Albrecht-Schgoer, Karin, Jonach, Verena, Koller, Bernhard, Lener, Daniela, Franz, Wolfgang M., Kirchmair, Rudolf
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781158/
https://ncbi.nlm.nih.gov/pubmed/24086307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074029
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