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The IRAK Homolog Pelle Is the Functional Counterpart of IκB Kinase in the Drosophila Toll Pathway

Toll receptors transduce signals that activate Rel-family transcription factors, such as NF-κB, by directing proteolytic degradation of inhibitor proteins. In mammals, the IκB Kinase (IKK) phosphorylates the inhibitor IκBα. A βTrCP protein binds to phosphorylated IκBα, triggering ubiquitination and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Daigneault, Jessica, Klemetsaune, Liv, Wasserman, Steven A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781037/
https://ncbi.nlm.nih.gov/pubmed/24086459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075150
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