Identification of New Drug Targets and Resistance Mechanisms in Mycobacterium tuberculosis

Identification of new drug targets is vital for the advancement of drug discovery against Mycobacterium tuberculosis, especially given the increase of resistance worldwide to first- and second-line drugs. Because traditional target-based screening has largely proven unsuccessful for antibiotic disco...

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Main Authors: Ioerger, Thomas R., O’Malley, Theresa, Liao, Reiling, Guinn, Kristine M., Hickey, Mark J., Mohaideen, Nilofar, Murphy, Kenan C., Boshoff, Helena I. M., Mizrahi, Valerie, Rubin, Eric J., Sassetti, Christopher M., Barry, Clifton E., Sherman, David R., Parish, Tanya, Sacchettini, James C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2013
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781026/
https://ncbi.nlm.nih.gov/pubmed/24086479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075245
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