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Generation of Human Induced Pluripotent Stem Cells in the Absence of Exogenous Sox2

Induced pluripotent stem cell technology has attracted enormous interests for potential application in regenerative medicine. Here, we reported that a specific glycogen synthase kinase 3 (GSK-3) inhibitor, CHIR99021, can induce the reprogramming of mouse embryonic fibroblasts (MEFs) transduced by on...

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Détails bibliographiques
Auteurs principaux: Li, Wenlin, Zhou, HongYan, Abujarour, Ramzey, Zhu, Saiyong, Joo, Jin Young, Lin, Tongxiang, Hao, Ergeng, Schöler, Hans R., Hayek, Alberto, Ding, Sheng
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780784/
https://ncbi.nlm.nih.gov/pubmed/19839055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.240
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