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An algorithm for chemical genomic profiling that minimizes batch effects: bucket evaluations

BACKGROUND: Chemical genomics is an interdisciplinary field that combines small molecule perturbation with traditional genomics to understand gene function and to study the mode(s) of drug action. A benefit of chemical genomic screens is their breadth; each screen can capture the sensitivity of comp...

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Bibliographic Details
Main Authors: Shabtai, Daniel, Giaever, Guri, Nislow, Corey
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780717/
https://ncbi.nlm.nih.gov/pubmed/23009392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-245
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