Prediction of Effective Drug Combinations by Chemical Interaction, Protein Interaction and Target Enrichment of KEGG Pathways

Drug combinatorial therapy could be more effective in treating some complex diseases than single agents due to better efficacy and reduced side effects. Although some drug combinations are being used, their underlying molecular mechanisms are still poorly understood. Therefore, it is of great intere...

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Bibliografische gegevens
Hoofdauteurs: Chen, Lei, Li, Bi-Qing, Zheng, Ming-Yue, Zhang, Jian, Feng, Kai-Yan, Cai, Yu-Dong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi Publishing Corporation 2013
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780555/
https://ncbi.nlm.nih.gov/pubmed/24083237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/723780
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