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Prediction of Effective Drug Combinations by Chemical Interaction, Protein Interaction and Target Enrichment of KEGG Pathways

Drug combinatorial therapy could be more effective in treating some complex diseases than single agents due to better efficacy and reduced side effects. Although some drug combinations are being used, their underlying molecular mechanisms are still poorly understood. Therefore, it is of great intere...

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Bibliografske podrobnosti
Main Authors: Chen, Lei, Li, Bi-Qing, Zheng, Ming-Yue, Zhang, Jian, Feng, Kai-Yan, Cai, Yu-Dong
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780555/
https://ncbi.nlm.nih.gov/pubmed/24083237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/723780
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