Prolonged Survival of Allogeneic Islets in Cynomolgus Monkeys After Short-Term Anti-CD154-Based Therapy: Nonimmunologic Graft Failure?

Conventional drug therapy and several anti-CD154 mAb-based regimens were tested in the nonhuman primate (NHP) islet allograft model and found to be inadequate because islets were lost to rejection. Short-term therapy with an optimized donor-specific transfusion (DST) + rapamycin (RPM) + anti-CD154 m...

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Main Authors:	Koulmanda, M., Smith, R.N., Qipo, A., Weir, G., Auchincloss, H., Strom, T.B.
Format:	Artigo
Sprog:	Inglês
Udgivet:	2006
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3779922/ https://ncbi.nlm.nih.gov/pubmed/16539625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2006.01235.x
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Prolonged Survival of Allogeneic Islets in Cynomolgus Monkeys After Short-Term Anti-CD154-Based Therapy: Nonimmunologic Graft Failure?

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