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Broadening the repertoire of functional herpes simplex virus type 1 (HSV-1)-specific CD8+ T cells reduces viral reactivation from latency in sensory ganglia()

A large proportion of the world population harbors herpes simplex virus type 1 (HSV-1) in a latent state in their trigeminal ganglia (TG). TG-resident CD8(+) T cells appear important for preventing HSV-1 reactivation from latency and recurrent herpetic disease. In C57BL/6J mice half of these cells a...

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Hlavní autoři: St. Leger, Anthony J, Jeon, Sohyun, Hendricks, Robert L
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779892/
https://ncbi.nlm.nih.gov/pubmed/23878317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300585
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