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Metabolic modulation of chromatin: implications for DNA repair and genomic integrity

The maintenance of genomic integrity in response to DNA damage is tightly linked to controlled changes in the damage-proximal chromatin environment. Many of the chromatin modifying enzymes involved in DNA repair depend on metabolic intermediates as cofactors, suggesting that changes in cellular meta...

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Bibliografiske detaljer
Main Authors: Liu, Jinping, Kim, Jeongkyu, Oberdoerffer, Philipp
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779809/
https://ncbi.nlm.nih.gov/pubmed/24065984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00182
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