Increased Expression of Fibroblast Growth Factor 21 (FGF21) during Chronic Undernutrition Causes Growth Hormone Insensitivity in Chondrocytes by Inducing Leptin Receptor Overlapping Transcript (LEPROT) and Leptin Receptor Overlapping Transcript-like 1 (LEPROTL1) Expression

During calorie restriction in mice, increased expression of FGF21 causes growth attenuation and growth hormone (GH) insensitivity. Previous evidence also indicates that fasting-associated increased expression of leptin receptor overlapping transcript (LEPROT) and LEPROT-like 1 (LEPROTL1) (two protei...

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Main Authors: Wu, Shufang, Grunwald, Tal, Kharitonenkov, Alexei, Dam, Julie, Jockers, Ralf, De Luca, Francesco
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779732/
https://ncbi.nlm.nih.gov/pubmed/23940039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.462218
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